Liu Yoko was born in Yokohama, Japan and studied at Tokyo College of Music. In 1993 she took part in the Aspen Music Festival (US) as a scholar and in 1995 she began studying with Professor François Benda at the Musik Akademie der Stadt Basel in Switzerland (she later graduated with a Soloist Diploma). She went on to perform with the Sinfonie Orchester Basel and as a trainee with the Radio Sinfonie Orchester Basel in 1996-7.
The following year, in July 1998, she was the soloist for a performance of a concerto by Gotkovsky with the Sinfonie Orchester Basel.
After returning to Japan, she began performing as a soloist in Tokyo, Yokohama and Fukuoka. She also performed with orchestras in Tokyo, Osaka and Kanazawa, among others. From 2001-05 she was a member of the Kyushu Symphony Orchestra. She joined the Singapore Symphony Orchestra in 2007.